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The Sanders and the Landrys are shaken when they learn that a disease called AIDS is threatening the country's blood supply; each family has boys with hemophilia, a genetic condition that means they depend on blood products to live.
Will fights to get those in charge of blood safety to heed the danger; the Landrys struggle to keep their family together; Dr. Christos Tsoukas publishes a study on hemophiliacs.
In 1985 Will Sanders questions why the Red Cross may still be distributing tainted blood when safe, heat-treated product is available; Margaret Sanders battles the prejudice surrounding AIDS.
After seven people are infected due to a company's heat-treating process, Jim Krepke joins the fight; Will scores a victory; Ben seeks direction; Alice and Peter try to separate from each other.
The Hemophilia Society works toward compensation for victims of tainted blood; Ryan suffers the side effects of hepatitis C treatment; Peter and Darby fall in love; Ben starts working on a more personal book.
Justice Horace leads an inquiry into the tainted blood scandal; Ben's quest for revenge intensifies; the people Krever intends to accuse, take him to court.
The court rules in favor of Krever, and his report that gives names is released.