Murray's sardonic Venkman, Ramis' uber-nerd Egon, and Aykroyd's easily distracted Ray are one of the most quotable comedy teams ever.
Just the sight of the Griswolds and their "Metallic Pea" station wagon should be enough to make you laugh.
When June Cleaver translates jive, you know you've got a winner on your hands.
A grown-man-in-a-doggie-door gag plus a "scorching case of herpes" equals comedy gold.
In one of the movie's funniest scenes, Chase and Murray bond over a joint made from the groundskeeper's special mix - of turf.
Who could forget Steve Martin's car rental tirade (using of the f-word 18 times in 60 seconds) or the diverted flight to Nowhere?
The mud-wrestling scene with John Candy getting his butt bitten (and beaten) by three blondes in bikinis is comedic legend.
There may be no more truly '80s movie moment than when Sean Penn (Spicoli) utters that most famous of stoner greetings, "Aloha Mr. Hand."
Hall's character may have never "bagged a babe," but he spouts some of the funniest lines of the movie.
McKean, Shearer and Guest improvise their parts to deadpan perfection.